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University of Alabama at Birmingham

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Directed by Dr. Kenneth G. Saag, the UAB Deep South Arthritis and Musculoskeletal Center for Education and Research on Therapeutics (CERTs) focuses on musculoskeletal disorders. Musculoskeletal disorders (MSD) impose a growing societal burden with many new therapeutic options, yet a considerable number of questions on effectiveness, efficiency, and equity of care remain unanswered. The UAB CERT studies the effectiveness and safety of therapies in MSD via patient centered outcomes research in both normal and disadvantaged or underserved populations; including racial and ethnic minorities, children, and older persons with associated medical conditions.

UAB CERT researchers are working to defining serious adverse events from biologic therapies using large administrative databases, conduct large pragmatic clinical trials, determine adherence to therapies, and reduce disparities in risk assessment and communication. The UAB CERT also emphasizes education of health care practitioners, patients, caregivers, payers, and policy makers while implementing and disseminating research and educational information about MSD therapeutics to improve public health.

The UAB CERT projects are:

  • Comparative effectiveness of NSAIDs versus narcotics after joint replacement surgery
  • A novel tool and multi-modal intervention for improving osteoporosis treatment adherence
  • Informed consent tools for pragmatic clinical trials in musculoskeletal diseases
  • Assessing comparative effectiveness of biologics and communicating risk in juvenile and adult inflammatory arthritis.

These items by the UAB CERT are posted on CHAIN Online:


Visit the University of Alabama at Birmingham Deep South Arthritis and Musculoskeletal CERT Web site.